1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azetidine-2-carboxylic acid
1-Fmoc-2-azetidinecarboxylic acid
CAS: 184763-07-3
Molecular Formula: C19H17NO4
1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azetidine-2-carboxylic acid - Names and Identifiers
1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azetidine-2-carboxylic acid - Physico-chemical Properties
| Molecular Formula | C19H17NO4 |
| Molar Mass | 323.34 |
1-{[(9H-fluoren-9-yl)methoxy]carbonyl}azetidine-2-carboxylic acid - Introduction
acid is an organic compound whose chemical structure contains an azetidine ring and a formic acid group. The following is a description of its nature, use, formulation and safety information:
Nature:
The acid is a white to yellowish crystal with good solubility. It is relatively stable at room temperature, but may decompose at high temperatures.
Use:
heavily acid is mainly used for protecting groups, linking agents and polymers in organic synthesis. Among them, Fmoc is a protective group, can protect the amino and hydroxyl and other reactive centers, used in organic synthesis step separation and protection.
Method:
The preparation of azo acid can be obtained by reacting 2-azetidine carboxylic acid with Fmoc-Cl. The specific steps are as follows:
1. Dissolve 2-azetidinecarboxylic acid in an organic solvent.
2. Slowly add the Fmoc-Cl and stir the reaction well.
3. The reaction system is filtered, washed and dried to obtain a crystalline product of acid.
Safety Information:
acid is generally relatively safe under normal conditions of use. However, it may be irritating to the skin, eyes and respiratory system, so personal protective measures such as wearing protective gloves, goggles and respiratory protection equipment are required during operation. In addition, ensure that it is stored in a cool, dry place and avoid mixing with oxidants and other chemicals.
Nature:
The acid is a white to yellowish crystal with good solubility. It is relatively stable at room temperature, but may decompose at high temperatures.
Use:
heavily acid is mainly used for protecting groups, linking agents and polymers in organic synthesis. Among them, Fmoc is a protective group, can protect the amino and hydroxyl and other reactive centers, used in organic synthesis step separation and protection.
Method:
The preparation of azo acid can be obtained by reacting 2-azetidine carboxylic acid with Fmoc-Cl. The specific steps are as follows:
1. Dissolve 2-azetidinecarboxylic acid in an organic solvent.
2. Slowly add the Fmoc-Cl and stir the reaction well.
3. The reaction system is filtered, washed and dried to obtain a crystalline product of acid.
Safety Information:
acid is generally relatively safe under normal conditions of use. However, it may be irritating to the skin, eyes and respiratory system, so personal protective measures such as wearing protective gloves, goggles and respiratory protection equipment are required during operation. In addition, ensure that it is stored in a cool, dry place and avoid mixing with oxidants and other chemicals.
Last Update：2024-04-09 20:52:54
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